- Cox was the first actor to portray Hannibal Lecter on his eponymous franchise.
- Cox played in Troy along with X-Men star Tyler Mane, X-Men: First Class star Rose Byrne and Deadpool 2 star Brad Pitt.
- Cox also portrayed Ivan Simanov in the comic adaptations Red and Red 2.
- Brian Cox also worked with Jed Rees in The Ringer.
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