Wolverine is captured by William Stryker and taken to Alkali Lake, for Weapon X.
After capturing Moira MacTaggert, Beast, Mystique and Quicksilver, William Stryker takes them to Alkali Lake. Scott Summers, Jean Grey and Kurt Wagner discover Logan (dubbed Weapon X), and Jean frees him with her powers as Logan/Weapon X attacks the guards. Meanwhile, Stryker escapes via helicopter while Logan tries to attack Scott and Kurt, although Jean calms him down and restores a part of his memory, just enough to give him sanity and allows him to escape into the wilderness.
The Weapon X Program is reopened by a secret government agency, it begin creating mutants through brutal and sadistic methods, to sell off to the highest bidder. Angel Dust and Ajax are among the first created, with the later becoming a doctor for the company.
Wade Wilson finds out he has terminal cancer. To save his life he agrees to an experimental procedure offered from Jared Smith. He is then taken to an Weapon X facility where he is tortured until his mutant gene emerges. After being put into a chamber that deprived him of oxygen, his mutant gene emerged and he was given enhanced abilities such as a healing factor.